The Muslim Brotherhood has pledged to "bring down Egypt's military coup" using peaceful means - as the number of people killed in clashes reportedly rose to 421.
The group, which backs ousted Islamist president Mohamed Morsi, made the statement as a month-long state of emergency was declared in the country.
It followed violence that was sparked when security forces stormed the Cairo protest camps supporting Mr Morsi
Brotherhood spokesman Gehad El Haddad wrote on his Twitter page: "We will always be non-violent and peaceful. We remain strong, defiant and resolved.
"We will push (forward) until we bring down this military coup."
Egypt's health ministry said the number of dead had reached 421 - which the interior ministry has said includes 43 police officers. Hundreds more have been injured. The Muslim Brotherhood claims more than 2,500 died.
Sky cameraman Mick Deane was killed in the violence Those killed included Sky cameraman Mick Deane, who was part of our team covering the unrest. He was shot on Wednesday morning.
The clashes spread from the capital to other parts of the country, including the Mediterranean city of Alexandria. A curfew from 7pm to 6am was declared in Cairo and 13 other provinces.
Hazem Al Beblawi, Egypt's Prime Minister, said he remained committed to the democratic process under a civilian state.
But he justified the use of force saying that Morsi loyalists had been sowing chaos around the country, "terrorising citizens, attacking public and private property".
"The state had to intervene to restore security and peace for Egyptians," he said. "No democratic country would impose an emergency state unless it is absolutely necessary."
The US was among a number of countries to have condemned the violence.
US Secretary of State John Kerry called the events "deplorable".
"Violence will not create a roadmap for Egypt's future. Violence only impedes the transition," he said.
He added that the promise of the 2011 revolution has not yet been fully realised.
Egypt's vice president, Mohamed ElBaradei, announced his resignation following the violence.
"It has become too difficult to continue bearing responsibility for decisions I do not agree with and whose consequences I fear," he said.
Sky's Middle East Correspondent Sam Kiley was reporting earlier from inside the Rabaa al Adawiya camp.
Describing the fighting he said: "I have covered many wars and this is as severe a battlefield as I have witnessed, with the exception of scenes in Rwanda.
"There are dozens and dozens of people who have been shot in the head, neck and upper body."
The unrest spread beyond the capital, as supporters of Mr Morsi clashed with police in the Nile Delta cities of Minya and Assiut, as police stations, government buildings and churches were attacked or set ablaze.
In Alexandria, tear gas canisters rained down on a pro-Morsi march in the Sharq neighbourhood, amid repeated bursts of automatic gunfire.
Residents armed with clubs came out of their homes and shops to help the police, detaining Morsi supporters and handing them over to officers at the Sharq police station.
Morsi supporters, carrying Egyptian flags and pictures of the deposed leader, then clashed with his opponents on a road carpeted with rocks.
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